R V Peters

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Seasonal changes of daylength (photoperiod) affect the expression of hormonal and behavioral circadian rhythms in a variety of organisms. In mammals, such effects might reflect photoperiodic changes in the circadian pace-making system [located in the suprachiasmatic nucleus (SCN) of the hypothalamus] that governs these rhythms, but to date no functionally(More)
In rodents, brief light pulses that shift the phase of the circadian locomotor rhythm also increase c-fos gene expression in the suprachiasmatic nucleus (SCN), site of an endogenous clock that regulates such rhythmicity. Because the magnitude of photic phase shifts varies when light pulses are applied at different time points over the course of the(More)
Ambient light alters the level of the transcriptional regulatory protein c-Fos in the suprachiasmatic nucleus, the site of an endogenous circadian clock in mammals, and in one other retino-recipient area, the intergeniculate leaflet of the lateral geniculate complex. Complementing previous work by ourselves and others on the photic and temporal regulation(More)
Several authors have suggested that the transcriptional regulatory protein c-Fos might be part of the mechanism for photic entrainment of the circadian pacemaker in the suprachiasmatic nucleus (SCN) to environmental light:dark cycles. This hypothesis has been based on evidence gathered using single light pulses administered acutely to animals free-running(More)
We measured immunoreactive Fos B protein levels in the ventrolateral subdivision of the rat suprachiasmatic nucleus (SCN) as a function of light and time of day. Immunohistochemistry revealed high levels of Fos B that were uniformly expressed throughout the 12 h:12 h light-dark cycle. Levels remained high in constant darkness and were modestly increased(More)
Vasoactive intestinal peptide (VIP) has been localized within the suprachiasmatic nucleus of the hypothalamus (SCN) and appears to play an important role in the entrainment of circadian rhythms with the light-dark (LD) cycle. The spontaneously hypertensive rat (SHR), an inbred strain used extensively in research on primary hypertension, has significantly(More)
Acknowledgmentss iii Listt of Figures vi Listt of Tables vii 11 Introduction 1 22 The Realized Volatility of the Main Dutch (AEX) Stock In-dexx 9 2.11 Introduction 9 2.22 Time-change and volatility 11 2.33 Description of the data 13 2.44 Testing on i.i.d. normality 15 2.55 The daily volatility cycle 23 2.66 Variability of volatility 27 2.77 Confrontation(More)