R T Fraser

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INTRODUCTION No detailed case studies report lateralised hypometabolism on positron emission tomography (PET) contralateral to the epileptogenic focus in temporal lobe epilepsy (TLE). MATERIAL AND METHODS We performed 18F fluorodeoxyglucose (FDG) PET in two intractable TLE patients. RESULTS One had right temporal interictal spikes on(More)
A 3 1/2-year-old boy developed partial complex seizures with right-sided motor activity, occasionally secondarily generalized at age 18 months. Initial EEG showed left-sided focal epileptiform discharges. Seizures became refractory to antiepileptic drugs (AEDs). At age 3 years, there was severe language deterioration consistent with Landau-Kleffner syndrome(More)
This article reviews the literature on rehabilitation outcome following epilepsy surgery to provide perspective on the research issues in examining vocational and independent living outcome. The existing literature does not suggest dramatic independent living or employment gains as a result of this surgery. Those most likely to profit in these areas are(More)
OBJECTIVE Determine rates of, and factors predictive of, return to work in patients with civilian traumatic head injuries. DESIGN Inception cohort study with 1- to 2-year follow-up. SETTING Hospitalized patients in a level I trauma center. PATIENTS Three hundred sixty-six hospitalized head-injured subjects who were workers before injury and 95(More)
BACKGROUND Mild traumatic brain injury (MTBI) is a significant public health problem affecting approximately 1 million people annually in the USA. A total of 10-15% of individuals are estimated to have persistent post-traumatic symptoms. This study aimed to determine whether focused, scheduled telephone counselling during the first 3 months after MTBI(More)
We examined, among those persons working preinjury, the risk of unemployment 1 year after traumatic brain injury (TBI) relative to expected risk of unemployment for the sample under a validated risk-adjusted econometric model of employment in the U.S. population. Results indicate that 42% of TBI cases were unemployed versus 9% expected, relative risk (RR) =(More)
Since the population with a traumatic brain injury is principally young with many years of potential future earning capacity, understanding the issues affecting the vocational outlook for this group is critical. This article overviews the research to date on vocational outcome, emphasizing newly developed multivariate prediction models and encouraging a(More)
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Interictal spikes on intraoperative electrocorticography during epilepsy are used to tailor resections. There have been a few systematic quantitative studies of anesthetic effects on these interictal discharges, and none on the effects of nitrous oxide (N2O). We calculated spike rates on ECoG on and off N2O in 18 epilepsy surgery patients with subdural(More)
Of 40 patients with cortical resections for epilepsy, three had focal suppression-burst (S-B) on postresection intraoperative electrocorticography (ECoG). Eighteen to 24 months later, two patients were seizure-free and one had rare seizures. Follow-up neuropsychological testing and MRI did not reveal unexpected postoperative abnormalities. Follow-up scalp(More)