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MOTIVATION Pathway Hunter Tool (PHT), is a fast, robust and user-friendly tool to analyse the shortest paths in metabolic pathways. The user can perform shortest path analysis for one or more organisms or can build virtual organisms (networks) using enzymes. Using PHT, the user can also calculate the average shortest path (Jungnickel, 2002 Graphs, Network(More)
The success of any nanoimprint process depends upon its ability to exactly reproduce the template pattern. Thus, complete filling of recessed features in the template is an important issue that is controlled by the dynamics of the flow through these sharp structures. At these small scales, capillary forces are large and must be included in the fluid flow(More)
Of 1202 hernia repairs performed according to the modified Lotheissen-McVay technique 1020 (84.9%) were followed up. The frequency of hernia increases with increasing age. The total recurrence rate after an average follow-up of 9 years was 9.2% for primary hernias and 11.5% for recurrences. The recurrence rate depends on the follow-up time and on sex. For(More)
Of 1202 hernia repairs performed according to the modified Lotheissen-McVay technique 1020 (84.9%) were followed up. The frequency of hernia increases with increasing age. The total recurrence rate after an average follow-up of 9 years was 9.2% for primary hernias and 11.5% for recurrences. The recurrence rate depends on the follow-up time and on sex. For(More)
Zur Analyse yon Ver~nderungen der KreislaufgrS~en unter Einwirkung eines Pharmakon ist eine gro~e Anzahl von Verfahren angegeben worden. Die groBe Gruppe tierexperimenteller Methoden hat den Vorteil direkter Mel3mSglichkeit bei blutigen Eingriffen. Die gewonnenen Ergebnisse miissen jedoch kritiseh geprfift werden, wenn man sie auf den Menschen iibertragen(More)
1. Durch Infusionsversuche nach Hatcher am Meerschweinchen mit und ohne Ausschaltung von Leber (einschließlich Darm) sowie Leber + Niere wurde gefunden, daß die Bindung von Herzglykosiden an die Leber in der Reihenfolge Digitoxin > Scillaren A > k-Strophanthin und die Bindung an die Niere in der Reihenfolge k-Strophanthin > Scillaren A > Digitoxin abnimmt.(More)