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A single dose of 0.05 mMol paraquat per kg body weight produced severe lesions in alveolar epithelial cells of type II and the capillary endothelial cells of rat lungs. The maximum damage pattern was seen after 48 hrs. Our results are in contrast to the general opinion in the literature, that paraquat leads to selective lesion of alveolar epithelial cells(More)
On the basis of a questionnaire the therapy of 2285 patients with tuberculosis was evaluated for the years 1987-1989. The data of the GDR National Tuberculosis Register (9827 patients) were used for statistical comparison. 85% of the patients had a pulmonary tuberculosis, 947 patients (41% of all) excreted tubercle bacilli in the sputum. The average(More)
On the occasion of the commemoration of the 100th anniversary of the discovery of the tubercle bacillus by Robert Koch, in 1982, it could be stated that in GDR, like in other developed countries, tuberculosis is not any more a serious problem of public health but has changed to a much reduced endemic disease. After evaluation of the most important(More)
The number of new cases of tuberculosis decreased hardly during the last seven years in the GDR. This is especially seen in the age group of 20 to 29 years. The percentage of immigrants with tuberculosis in the age group named above increased from 24% (1982) to 41% (1988). Special attention is to pay to the case finding of tuberculosis among the GDR(More)
The article is an epidemiologic review of the situation in the German Democratic Republic with regard to tuberculosis. Conclusions for the future strategy to fight tuberculosis are drawn. During the past few years the drop in the incidence of tuberculosis, especially of bacillary pulmonary tuberculosis, is no longer as marked as it had been previously.(More)