Learn More
Asbestos, a class of fibrous mineral silicates found in nature, is carcinogenic to both man and experimental animals. Throughout the years, there has been extensive documentation of health problems posed by the fibres. Asbestos workers show a high incidence of asbestosis of lung More recently, numerous epidemiological and clinical studies have firmly(More)
Modification of sister chromatid exchanges and radiation-induced transformation in mouse C3H/10T 1/2 and Syrian hamster embryo cells by the tumor promoter 12-O-tetradecanoylphorbol-13-acetate and two retinoids, the trimethylmethoxyphenyl analog of N-ethyl retinamide and beta-all-trans-retinoic acid, has been studied. 12-O-tetradecanoylphorbol-13-acetate(More)
The in vitro cytotoxicity and oncogenic potential of both native and acid leached asbestos fibres were studied using the C3H 10T1/2 cell model. Both native and leached fibres induced a dose-dependent toxicity. At high fibre concentrations, acid leached fibres were significantly less toxic than their untreated counterparts. While asbestos fibres alone do not(More)
  • 1