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A new database of conserved amino acid residues is derived from the multiple sequence alignment of over 84 families of protein sequences that have been reported in the literature. This database contains sequences of conserved hydrophobic core patterns which are probably important for structure and function, since they are conserved for most sequences in… (More)
A new secondary structure prediction algorithm (SecondaryPlot) is described and has been developed for the IBM or compatible computer. This algorithm successfully predicts the boundaries of secondary structural regions by combining hydrophilicity, accessibility and flexibility parameters. Within the limits of these predicted structural regions, five… (More)