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OBJECTIVES The incidence of prostate cancer is increasing, as is the number of diagnostic and therapeutic interventions to manage this disease. We developed a Markov state-transition model--the Montreal Prostate Cancer Model--for improved forecasting of the health care requirements and outcomes associated with prostate cancer. We then validated the model by(More)
BACKGROUND We developed an economic model of prostate cancer management from diagnosis until death. We have used the Montreal Prostate Cancer Model to estimate the total economic burden of the disease in a cohort of Canadian men. METHODS Using this Markov state-transition simulation model, we estimated the probability of prostate cancer, annual prostate(More)
Capecitabine, an oral prodrug of 5-fluorouracil (5FU), has been integrated into the management of multiple cancer types because of convenience of administration and efficacy comparable with 5fu. Cardiotoxicity induced by 5FU-in particular angina-has been well described in the literature, but reports of adverse cardiac events with capecitabine are also(More)
The annual Eastern Canadian Colorectal Cancer Consensus Conference was held in Montreal, Quebec, October 22-24, 2009. Health care professionals involved in the care of patients with colorectal cancer participated in presentation and discussion sessions for the purposes of developing the recommendations presented here. This consensus statement addresses(More)
3656 Background: The costs of managing stage 3 and 4 colorectal cancer patients were determined and correlated with baseline patient characteristics. METHODS All patients presenting with stage 3 or 4 colorectal cancer at our institution between January 1986 and December 1993 were identified. Patients without pathologic confirmation or treated elsewhere(More)
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