R R Koegel

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The annual incidence of end-stage renal disease (ESRD: 1.32 patients aged 1/2-16 years per million population or 6.5 per million children of same age) and the causes have remained remarkably constant over the last 15 years in Switzerland. 58 patients (69%) were treated by dialysis and/or renal transplantation. The overall survival rate was 77% at 5 years(More)
In 14 patients with fixed and reproducible postural proteinuria and 14 patients with histologically proven glomerulonephritis, the selectivity of proteinuria was measured separately in the day and night urine collections. The selectivity of proteinuria in the urine collected in recumbency was lower in patients with glomerulonephritis than in patients with(More)
78 cases of double kidneys without vesico-uretero-renal reflux, in which a heminephrectomy was done, were histologically investigated. The histopathological results were compared with the clinic and the urogram. It could be demonstrated that the results did not correspond in some cases. As a consequence of these discrepancies, we conclude that intravenous(More)
In studies on human skin fibroblasts originating from three patients with Bartter's syndrome and in corresponding age and sex matched controls, the bradykinin stimulated release of PGE2, PGI2, PGF2 alpha and of arachidonic acid was examined. The studies were aimed at demonstrating the possible changes of prostaglandin production under the influence of(More)
In order to differentiate lower from upper urinary tract infection (UTI) we have studied 40 children with clinical, haematological and bacteriological findings suggestive of UTI. The methods used included quantitative measurement of C reactive protein (CrP), erythrocyte sedimentation rate (ESR) and antibody coating of urinary bacteria (ACB) using a(More)