R R Gritzke

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The present study examined the effects of an acute psychoactive dose of cocaine hydrochloride (HCl) in the rat, using the brain-stem auditory evoked potential (BAEP) as an objective, quantitative measure of this substance's effects on brain and auditory electrophysiology. The animals were 8 adult Long-Evans rats (4 female, 4 male). BAEPs were recorded from(More)
Because ketamine is both an abused substance and a commonly used veterinary anesthetic, its effects on brain and sensory functions are of interest. The present study examined the dose-dependent effects of ketamine anesthesia in the rat, using the brain-stem auditory evoked potential (BAEP) as an objective, quantitative measure of this substance's acute(More)
Because brainstem auditory evoked potentials (BAEPs) are frequently recorded in anesthetized animals and humans, it is important to become familiar with the effects on the BAEP of drugs used during anesthesia, including pre-anesthetics. The dose-dependent and stimulus intensity-dependent effects on the BAEP of a pre-anesthetic, atropine sulfate, were(More)
In goldfish the heart rate orienting response to periodic photic stimuli was measured by a specially designed computer that also regulated the intensity of the stimuli to maintain the response. When ethanol was administered, the fish then exhibited orienting responses to less intense stimuli; this increased excitability was maintained for the duration of(More)
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