R Paul Johnson

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Associations between known or putative virulence factors of Shiga toxin-producing Escherichia coli and disease in humans were investigated. Univariate analysis and multivariate logistic regression analysis of a set of 237 isolates from 118 serotypes showed significant associations between the presence of genes for intimin (eae) and Shiga toxin 2 (stx2) and(More)
Human and simian immunodeficiency virus (HIV and SIV) replicate optimally in activated memory CD4(+) T cells, a cell type that is abundant in the intestine. SIV infection of rhesus monkeys resulted in profound and selective depletion of CD4+ T cells in the intestine within days of infection, before any such changes in peripheral lymphoid tissues. The loss(More)
Allan J. Collins, MD, Robert N. Foley, MB, Charles Herzog, MD, Blanche Chavers, MD, David Gilbertson, PhD, Areef Ishani, MD, MS, Bertram Kasiske, MD, Jiannong Liu, PhD, Lih-Wen Mau, PhD, Marshall McBean, MD, MSc, Anne Murray, MD, MSc, Wendy St. Peter, PharmD, Haifeng Guo, MS, Sally Gustafson, MS, Qi Li, MS, ShuLing Li, MS, Suying Li, PhD, Yi Peng, MS, Yang(More)
RICHARD JOHNSON, JAMES PANKOW, DAVID BENDER, CURTIS PRICE, AND JOHN ZOGORSKI T he increasing frequency of detection of the widely used gasoline additive methyl tertbutyl ether (MTBE) in both groundand surface waters is receiving much attention from the media, environmental scientists, state environmental agencies, and federal agencies. At the national(More)
Kaposi's sarcoma-associated herpesvirus (KSHV) K3 and K5 proteins dramatically downregulate MHC class I molecules. However, although MHC class I downregulation may protect KSHV-infected cells from cytotoxic T lymphocyte recognition, these cells become potential targets for natural killer (NK) cell-mediated lysis. We now show that K5 also downregulates(More)