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This paper briefly considers the notion of a biology of quantum information from a number of complementary points of view. We begin with a very brief look at some of the biomolecular systems that are thought to exploit quantum mechanical effects and then turn to the issue of measurement in these systems and the concomitant generation of information. This(More)
A number of viewpoints on how a cell can be modelled are discussed in this paper in light of the ability it has to process information. The paper begins with a very brief summary of four general types of computation: sequential, parallel, distributed, and emergent. These form the general framework from which a number of comparisons are made. Several(More)
In eucaryotic organisms, responses to external signals are mediated by a repertoire of intracellular signalling pathways that ultimately bring about the activation/inactivation of protein kinases and/or protein phosphatases. Until relatively recently, little thought had been given to the intracellular distribution of the components of these signalling(More)
This paper presents two approaches to the individual-based modelling of bacterial ecologies and evolution using computational tools. The first approach is a fine-grained model that is based on networks of interactivity between computational objects representing genes and proteins. The second approach is a coarser-grained, agent-based model, which is(More)
One of the key phases in Knowledge Based Systems (KBS) construction is Knowledge Acquisition. However, human knowledge about domains is so complex that without an analysis stage that probes the underlying nature of the real world problem and how human experts conceptualise it, the knowledge incorporated within a KBS remains shallow and incomplete. In this(More)
1. Introduction Malaria kills around 2 million people per year, predominantly attributable to P. falciparum infection of children in sub-Saharan African. Interventions such as the provision of bednets, or mass treatment with antimalarial drugs, which reduce the impact of malaria, generally reduce all-cause childhood mortality by 25-33%, suggesting that(More)