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MRI tractography is the mapping of neural fiber pathways based on diffusion MRI of tissue diffusion anisotropy. Tractography based on diffusion tensor imaging (DTI) cannot directly image multiple fiber orientations within a single voxel. To address this limitation, diffusion spectrum MRI (DSI) and related methods were developed to image complex… (More)
Objective To perform serial in-vivo diffusion tensor MRI (DTI) and tractography of the mouse heart and characterize the impact of ischemia on myocardial microstructure.