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We have studied the effects of two endotoxins, S enteritidis and E coli on liver, pancreas, intestine, lung and kidney of 10 day old Sprague Dawley rat at light and electron microscope levels. One group of experimental animals (N = 31) received a single intraperitoneal injection of 0.1 mg/kg of S enteritidis endotoxin. The second experimental group (N = 34)(More)
Sepsis in newborns and infants is a major pediatric problem often associated with renal dysfunction. The present report deals with changes in renal tissue induced by Salmonella enteritidis endotoxin in 10- and 28-day-old Sprague-Dawley rats. Our studies revealed a 90% lethality within 24 h of 0.1 mg/kg and 35 mg/kg S. enteritidis endotoxin injection in 10-(More)
— As most validation engineers know through experience, the tapeout of a chipset design does not mean the end of " pre-silicon " validation efforts. Silicon debug will always discover various issues that were missed during validation, and new customer requirements may be discovered that need to be integrated into the next stepping. So, after the initial (or(More)
Even with the presence of modern obstetric care, stillbirth rate seems to stay stagnant or has even risen slightly in countries such as England and has become a significant public health concern [1]. In the light of current medical research, maternal risk factors such as diabetes and hypertensive disease were identified as possible risk factors and are(More)
Antisera to the streptococcal cell membrane (SCM) were evaluated for their reactivity to murine glomerular basement membrane (GBM) in four strains of mice. Animals were studied on a daily basis from birth through 3 months and weekly thereafter through 18 months. Paired animals were compared for in vivo binding of antibody versus an indirect fluorescent(More)
Incorporation of 3H-proline in the mouse kidney was studied by electron microscopic radioautography in a pulse-chase mode to establish the role of visceral epithelial, endothelial, and mesangial elements in the synthesis and turnover of glomerular basement membrane. Visceral epithelial and endothelial cells were found to play a significant role in the(More)
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