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Metacognitive awareness is a cognitive set in which negative thoughts/feelings are experienced as mental events, rather than as the self. The authors hypothesized that (a) reduced metacognitive awareness would be associated with vulnerability to depression and (b) cognitive therapy (CT) and mindfulness-based CT (MBCT) would reduce depressive relapse by(More)
Recent research has suggested that depressive biases in personal memory may be due to an inability to progress beyond a general level when trying to retrieve specific positive memories. This study produced further evidence of this phenomenon. When trying to access specific hedonically toned memories, depressed patients more often responded with a general(More)
This paper reports the trial of a wearable data capture device, SenseCam, as a resource for digital narratives and uses data from the trial to reflect on the models of the 'mind' that underscore HCI. More particularly, over a period of one week, 5 participants and 2 researchers used SenseCams to capture digital traces of their experiences, and used the same(More)
Obtaining accurate percutaneous renal access when treating intrarenal disease requires substantial skill. Robotic devices have been used in a variety of surgical applications and have been successful in facilitating percutaneous puncture while improving accuracy. Laboratory models of robotic devices for percutaneous renal access have also been developed.(More)
This paper reports the trial of a memory prosthesis, SenseCam, as a resource for digital narratives. Over a period of one week, six participants were asked to use SenseCams to capture digital traces of their experiences, and to use the same to create 'story telling' materials for presentation. The study found that all users delighted in the devices, though(More)
Our recent study showed that tetrathiomolybdate (TM), a drug to treat copper overload disorders, can sensitize drug-resistant endometrial cancer cells to reactive oxygen species (ROS)-generating anticancer drug doxorubicin. To expand these findings in the present study we explore TM efficacy in combination with a spectrum of ROS-generating anticancer drugs(More)
Antiestrogens including tamoxifen and fulvestrant have been evaluated as chemotherapeutics for ovarian cancer, particularly in cases of platinum resistant disease. Human epididymis protein 4 (HE4) is highly overexpressed in women with ovarian cancer and overexpression of HE4 has been found to correlate with platinum resistance. However, the role of HE4 in(More)