R Montjean

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Nephronophthisis, a hereditary nephropathy characterized by interstitial fibrosis and cyst formation, is caused by mutations in NPHP genes encoding the ciliary proteins called nephrocystins. We investigate the function of nephrocystin-1,-4 and-8, in vitro and in vivo in mamma-lian kidney cells and in zebrafish respectively. Depletion of either NPHP1(More)
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