R Mikulová

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A high fasting respiratory quotient (RQ) was observed during the treatment by very low calorie diet (VLCD) in obese patients who regained weight at two-year follow-up (weight regainers) or in those who exhibited repeated cycles of weight loss with a subsequent weight regain (weight cyclers). In contrast obese patients who succeeded to retain the weight loss(More)
The first aim of the present study was to evaluate the changes in serum levels of cortisol, testosterone, dehydroepiandrosterone (DHEA), dehydroepiandrosterone sulphate (DHEA-S) and sex hormone-binding globulin (SHBG) in response to weight loss induced by one month of treatment with a very low-calorie diet (VLCD) in twelve pairs of female obese monozygotic(More)
Fasting plasma levels of both cortisol and sex hormone binding globulin (SHBG) in obese women were significantly inversely related to anthropometric characteristics of body fat distribution. It means that a central accumulation of body fat might be partly mediated by cortisol and SHBG levels. Significant within-pair resemblance observed in plasma cortisol(More)
Adipose tissue distribution predicts development of obesity complications better than total adipose tissue content. The aim of the study was to evaluate the role of the hormonal factors contributing to the adipose tissue distribution in obese females. The cohort examined consisted of 94 women in the range of overweight to obesity, aged 44.2 +/- 11.2 years(More)
Uncoupling proteins are located in the inner mitochondria membrane. Their name is derived from their function: they uncouple oxidative procesess of the respiratory chain from ATP synthesis. Hitherto several members of the family have been described, the best known being UCP1. UCP1 can be expressed exclusively in brown adipose tissue and it is responsible(More)
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