R. Martin

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This paper proposes a novel method for blindly separating unobservable independent component (IC) signals based on the use of a genetic algorithm. It is intended for its application to the problem of blind source separation (BSS) on post-nonlinear mixtures. The paper also includes a formal proof on the convergence of the proposed algorithm using guiding(More)
Objectives The period of post-operative treatment before surgical wounds are completely closed remains a key window, during which one can apply new technologies that can minimise complications. One such technology is the use of negative pressure wound therapy to manage and accelerate healing of the closed incisional wound (incisional NPWT). Methods We(More)
BCNU (carmustine), VM26 (teniposide) and ARA-A5'P (vidarabin-monophosphate) were compared in their activity against 30 cell lines of primary (N = 21) and metastatic (N = 9) human brain tumours, which were characterized in tissue culture by cytochemical, immunological and cytogenetic criteria. In vivo achievable concentration-time products c X t were(More)
  • S. J. Loyd, J. Sample, R. E. Tripati, W. F. Defliese, K. Brooks, M. Hovland +6 others
  • 2016
Methane cold seep systems typically exhibit extensive buildups of authigenic carbonate minerals, resulting from local increases in alkalinity driven by methane oxidation. Here, we demonstrate that modern seep authigenic carbonates exhibit anomalously low clumped isotope values (Δ47), as much as ∼0.2‰ lower than expected values. In modern seeps, this range(More)
BACKGROUND Atrial fibrillation is associated with higher mortality. Identification of causes of death and contemporary risk factors for all-cause mortality may guide interventions. METHODS AND RESULTS In the Rivaroxaban Once Daily Oral Direct Factor Xa Inhibition Compared with Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial(More)
  • M. Auais, S. Morin, L. Finch, A. Sara, N. Mayo, A. Charise +227 others
  • 2012
Objectives: To identify current practices and care gaps for elderly patients admitted following a hip fracture, and to characterize patients' patterns of functional recovery over 1-year. Relevance Increased awareness of existing gaps and improving our understanding of patients' recovery can help optimize patients' outcomes. Methods: Forty community-dwelling(More)