The 'excitability' and 'conductivity' of motor pathways during transcranial stimulation (TCS) have been investigated in 49 patients affected by multiple sclerosis (34), amyotrophic lateral sclerosis (7), spino-cerebellar ataxia (3), primary lateral sclerosis (4) and brain metastasis (1). Hyper-reflexia, spasticity and weakness were correlated with the… (More)
The interval between muscle stretch and the onset of the long latency electromyographic responses (LLRs) has been theoretically fragmented into an afferent time (AT), taken at the peak of wave N20 of somatosensory evoked potentials and an efferent time (ET), calculated by means of magnetic transcranial stimulation (TCS), the two being separated by a… (More)
The rare combination of progressive facial hemiatrophy, linear scleroderma and spasm of the homolateral masseter muscle was observed in a 39 year old woman. The possible pathogenetic meaning of the association is discussed on the electrophysiological evidence and in the light of published cases.
Single fibre motor evoked potentials to magnetic and electric non-invasive stimulation of brain, spinal cord and peripheral nerve were recorded in 8 healthy volunteers. The 'central motor jitter' and the 'peripheral motor jitter' were respectively calculated and a comparison between the magnetic and electric modalities was made. The highest degree of… (More)
Bit-colour maps of somatosensory evoked potentials (SEPs) and muscular responses from forearm and hand muscles were simultaneously recorded after median nerve stimulation. Subjects were asked either to relax totally (A), or to contract the examined muscle continuously and isometrically at 10-20% (B) and 80-100% (C) of the maximal strength. Isotonic… (More)
A segmental monosynaptic reflex that can be evoked by using voluntary muscle contraction to facilitate it is of use in diagnosis. In a group of 15 healthy volunteers the reflex response from tibialis anterior proved to be 31.08 +/- 2.48 msec with a side difference of 0.41 +/- 0.36 msec and from peroneus longus 29.90 +/- 2.20 msec with a side difference of… (More)
In a 49 year old woman an injury to the right frontotemporal region was quickly followed first by paresis and then by spasm of the right side of the face. The early onset of the spasm prompts a critical review of current views on the pathogenesis of facial spasm.
Two cases of mitochondrial myopathy are described. An electrophysiological study was also accomplished to investigate the concomitant involvement of the central nervous system (CNS), by means of evoked potentials (EP). The EPs in fact can reveal minimal signs of CNS lesions also when muscular damage is the only clinical evidence.
Three clinical cases of essential blepharospasm are discussed. On the basis of both therapeutical results and a review of the literature, pathogenetic hypothesis concerning such pathology are reexamined.