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To assess neurochemical and neuroanatomical correlates of age and spatial learning, aged Sprague-Dawley male rats (20-22 mo) were divided into two groups based on their ability to locate a hidden platform in a Morris water maze. An "old good" group of rats acquired the task as rapidly as young (3-6 mo) animals, whereas an "old poor" group of rats failed to(More)
The entire dorsal and lateral cortex of one cerebral hemisphere of rats was infiltrated with different fluorescent tracers and the neostriatum was examined for labelled perikarya. In spite of the extensive infiltration of the cortex, such neurons were seen only sporadically in the ipsilateral neostriatum and almost only in the vicinity of the globus(More)
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