R Linnartz

Learn More
BACKGROUND To study the molecular mechanism regulating sensitivity to MEK inhibition in pancreatic cancer cell lines. METHODS A growth inhibition assay determined sensitivity to MEK162 in a panel of 29 pancreatic cancer cell lines. For the same panel, KRAS mutational status and copy-number variation (CNV) was determine using PCR, array CGH and FISH. Two(More)
  • 1