Sort by:

• Highly Influential Citations
• Citations
• Acceleration
• Velocity
• Recency

Learn More

Control of conformational equilibria in the human B2 bradykinin receptor. Modeling of nonpeptidic ligand action and comparison to the rhodopsin structure.

• Jacky Marie, Eric J. Richard, +8 authors Jean C Bonnafous
• The Journal of biological chemistry
• 2001

A prototypic study of the molecular mechanisms of activation or inactivation of peptide hormone G protein-coupled receptors was carried out on the human B2 bradykinin receptor. A detailed… (More)

Mutation of Asn111 in the third transmembrane domain of the AT1A angiotensin II receptor induces its constitutive activation.

• Thierry Groblewski, Bernard Maigret, R Larguier, Colette Lombard, Jean C Bonnafous, Jacky Marie
• The Journal of biological chemistry
• 1997

A preliminary model of the rat AT1A angiotensin II (AII) receptor (Joseph, M. P., Maigret, B., Bonnafous J.-C., Marie, J., and Scheraga, H. A. (1995) J. Protein Chem. 14, 381-398) has predicted an… (More)

Tyr292 in the seventh transmembrane domain of the AT1A angiotensin II receptor is essential for its coupling to phospholipase C.

• Jacky Marie, Bernard Maigret, +4 authors Jean C Bonnafous
• The Journal of biological chemistry
• 1994

An essential role of the conserved Asp74 in the coupling of the type 1 angiotensin II (AII) receptor (AT1) to phospholipase C has already been reported (Bihoreau, C., Monnot, C., Davies, E., Teutsch,… (More)

Constitutive activation of the human bradykinin B2 receptor induced by mutations in transmembrane helices III and VI.

• Joelle Marie, Christian Koch, +7 authors Jean C Bonnafous
• Molecular pharmacology
• 1999

We report that mutation of specific residues in the human B2 bradykinin (BK) receptor induces its marked constitutive activation, evaluated through inositol phosphate production in COS-7 cells… (More)

N-glycosylation requirements for the AT1a angiotensin II receptor delivery to the plasma membrane.

• Benoit Deslauriers, Carlos A Oral Ponce, Colette Lombard, R Larguier, Jean C Bonnafous, Jacky Marie
• The Biochemical journal
• 1999

The purpose of this work was to investigate the role of N-glycosylation in the expression and pharmacological properties of the the rat AT1a angiotensin II (AII) receptor. Glycosylation-site… (More)

Deglycosylation and fragmentation of purified rat liver angiotensin II receptor: application to the mapping of hormone-binding domains.

• F Desarnaud, Jacky Marie, +5 authors Jean C Bonnafous
• The Biochemical journal
• 1993

We report new structural data about the rat liver angiotensin II receptor, which belongs to the AT1 subclass. This receptor has been purified at analytical or semi-preparative levels by a previously… (More)

Amino acids of the third transmembrane domain of the AT1A angiotensin II receptor are involved in the differential recognition of peptide and nonpeptide ligands.

• Thierry Groblewski, Bernard Maigret, +4 authors Jacky Marie
• Biochemical and biophysical research…
• 1995

The differential role of amino acids of the third transmembrane domain on peptide and nonpeptide recognition by the AT1 angiotensin II receptor has been evidenced. The mutation of Ser105 into alanine… (More)

Properties of [3H]LF 7-0156, a new nonpeptide antagonist radioligand for the type 1 angiotensin II receptor.

• S Nouet, Pierre Dodey, +5 authors Jean C Bonnafous
• Molecular pharmacology
• 1994

LF 7-0156 (2-[[[2-butyl-1-[(4-carboxyphenyl)methyl]-1H-imidazol- 5-yl]methyl]amino]benzoic acid) is a nonpeptide angiotensin II receptor antagonist selective for the type 1 angiotensin receptor. In… (More)

Lymphocyte mitogenesis and CD4 modulation induced by different phorbol esters: comparative studies.

• Jean Favero, Jeanne Dixon, Philippe C Bishop, R Larguier, John W. Parker
• International journal of immunopharmacology
• 1990

Phorbol 12-myristate 13-acetate (PMA) can stimulate T-cells via its binding to protein kinase C (PKC). Such a phenomenon occurs when a threshold of concentration as low as 1 nM of PMA is reached.… (More)

Specific nonpeptide photoprobes as tools for the structural study of the angiotensin II AT(1) receptor.

• S Nouet, Pierre Dodey, +9 authors Jean C Bonnafous
• Journal of medicinal chemistry
• 1999

The aim of this work was to obtain photoactivatable nonpeptide antagonists of the angiotensin II AT(1) receptor. Based on structure-function relationships, two chemical structures as well as… (More)

• ‹
• 1
• 2
• ›