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Exposure to methyl mercury, a risk factor for neurodevelopmental toxicity, was assessed in U.S. children 1-5 years of age (n = 838) and women 16-49 years of age (n = 1,726) using hair mercury analysis during the 1999-2000 National Health and Nutrition Examination Survey (NHANES). The data are nationally representative and are based on analysis of(More)
OBJECTIVE This study was designed to determine whether prenatal mercury exposure, including potential releases from the World Trade Center (WTC) disaster, adversely affects fetal growth and child development. METHODS We determined maternal and umbilical cord blood total mercury of nonsmoking women who delivered at term in lower Manhattan after 11(More)
SMART (http://www.cs.wm.edu/ ciardo/SMART/) is a software package integrating logic and stochastic modeling formalisms into a single environment. Models expressed in different formalisms can be combined in the same study. To study logical behavior, both explicit and symbolic state-space generation techniques, as well as CTL modelchecking algorithms, are(More)
OBJECTIVES To evaluate trends in children's blood lead levels and the extent of blood lead testing of children at risk for lead poisoning from national surveys conducted during a 16-year period in the United States. METHODS Data for children aged 1 to 5 years from the National Health and Nutrition Examination Survey III Phase I, 1988-1991, and Phase II,(More)
OBJECTIVE To provide levels of total and speciated urinary arsenic in a representative sample of the US population. METHODS For the first time, total arsenic and seven inorganic and organic arsenic species were measured in the urine of participants (n=2557) for the 2003-2004 National Health and Nutrition Examination Survey (NHANES). Data were compiled as(More)
BACKGROUND Mercury amalgam dental restorations have been used by dentists since the mid 19th century and issues on safety continue to be periodically debated within the scientific and public health communities. Previous studies have reported a positive association between urine mercury levels and the number of dental amalgams, but this relation has never(More)
Humans are exposed to many environmental chemicals, some of which can potentially affect neurodevelopment. Fetuses, infants, and young children are the most susceptible to the effects of these chemicals. As part of the National Health and Examination Survey, 1999-2000, the Centers for Disease Control and Prevention analyzed biological samples for many of(More)
We describe the main features of SmArT, a software package providing a seamless environment for the logic and probabilistic analysis of complex systems. SmArT can combine different formalisms in the same modeling study. For the analysis of logical behavior, both explicit and symbolic state-space generation techniques, as well as symbolic CTL model-checking(More)
The quantification of greenhouse gases present in the Archaean atmosphere is critical for understanding the evolution of atmospheric oxygen, surface temperatures and the conditions for life on early Earth. For instance, it has been argued that small changes in the balance between two potential greenhouse gases, carbon dioxide and methane, may have dictated(More)
CONTEXT Humans are exposed to methylmercury, a well-established neurotoxin, through fish consumption. The fetus is most sensitive to the adverse effects of exposure. The extent of exposure to methylmercury in US women of reproductive age is not known. OBJECTIVE To describe the distribution of blood mercury levels in US children and women of childbearing(More)