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The kelch motif was discovered as a sixfold tandem element in the sequence of the Drosophila kelch ORF1 protein. The repeated kelch motifs predict a conserved tertiary structure, a beta-propeller. This module appears in many different polypeptide contexts and contains multiple potential protein-protein contact sites. Members of this growing superfamily are(More)
N-Acetylcysteine (NAC), being both a mucolytic agent and a thiol-containing antioxidant, may affect the establishment and maintenance of H. pylori infection within the gastric mucus layer and mucosa. Agar and broth dilution susceptibility tests determined the MIC of H. pylori strain SSI to NAC. H. pylori load in SSI strain-infected C57BL mice was determined(More)
In a chamber of the heart, large-scale vortices are shown to exist as the result of the dynamic blood flow and unique morphological changes of the chamber wall. As the cardiovascular flow varies over a cardiac cycle, there is a need for a robust quantification method to analyze its vorticity and circulation. We attempt to measure vortex characteristics by(More)
Cardiovascular diseases can be diagnosed by assessing abnormal flow behavior in the heart. We introduce, for the first time, a magnetic resonance imaging-based diagnostic that produces sectional flow maps of cardiac chambers, and presents cardiac analysis based on the flow information. Using steady-state free precession magnetic resonance images of blood,(More)
MOTIVATION The sensitivity and specificity of branched DNA (bDNA) assays are derived in part through the judicious design of the capture and label extender probes. To minimize non-specific hybridization (NSH) events, which elevate assay background, candidate probes must be computer screened for complementarity with generic sequences present in the assay. (More)
Phase contrast magnetic resonance imaging is performed to produce flow fields of blood in the heart. The aim of this study is to demonstrate the state of change in swirling blood flow within cardiac chambers and to quantify it for clinical analysis. Velocity fields based on the projection of the three dimensional blood flow onto multiple planes are scanned.(More)
BACKGROUND Motion tracking based on spatial-temporal radio-frequency signals from the pixel representation of magnetic resonance (MR) imaging of a non-stationary fluid is able to provide two dimensional vector field maps. This supports the underlying fundamentals of magnetic resonance fluid motion estimation and generates a new methodology for flow(More)
Injuries are common within military populations, with high incidence rates well established in the literature. Injuries cause a substantial number of working days lost, a significant cost through compensation claims and an increased risk of attrition. In an effort to address this, a considerable amount of research has gone into identifying the most(More)
Patients with an atrial septal defect (ASD) have a left to right shunt with associated complications. Currently, various imaging modalities, including echocardiography and invasive cardiac catheterization, are utilized in the management of these patients. Cardiac magnetic resonance (CMR) imaging provides a novel and non-invasive approach for imaging(More)
A fish-inspired heaving and pitching foil was investigated in a water tunnel using dye visualisation, at Reynolds numbers between 870 and 3480 (based on the chord length) and Strouhal numbers between 0.06 and 1.37. The variation of the wake pattern with respect to the Strouhal number was investigated. Three different wake regimes were observed-a drag wake,(More)