R. Jones

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A method is proposed for eeciently computing moving average lters in regular octagonal windows, as approximations to circular windows. The algorithm requires thirteen operations per pixel irrespective of window size and is faster than existing Fourier-based and recursive methods for all but the smallest windows. Further, new variance-weighted nonlinear(More)
A method is described for finding all occurrences of a sequence pattern within a database of molecular sequences. Implementation of this on a massively parallel computer allows the user to perform very fast database searches using complex patterns. In particular, the software supports approximate pattern matching with score thresholds for either the entire(More)
Gastroesophageal reflux disease (GERD) is a common problem in the community and in general practice. General practitioners and family physicians need to understand patients' reasons for consultation and also be aware of alarm symptoms suggestive of serious disease. A primary care management strategy for GERD is proposed, in which the place of endoscopic and(More)
PURPOSE One approach to identify genes that contribute to common complex ocular disorders such as primary open angle glaucoma (POAG) is to study the genetic determinates of endophenotypes that are defined by underlying pre-disposing heritable quantitative traits such as central corneal thickness (CCT). Collagen VIII is a major component of Descemet's(More)
Sulfur dioxide (SO2) is a well-known and widespread air pollutant but it also acts as signaling molecule in various processes in animals. However, there is limited information on the role of SO2 in plants except of its toxicity. Here we studied the role of SO2 on stomatal movements in sweet potato (Ipomoea batatas) leaves. SO2, generated by Na2SO3/NaHSO3(More)
OBJECTIVE To influence the planning of the 2014 Commonwealth Games such that the positive impacts are maximized and the negative impacts are mitigated. STUDY DESIGN Participatory health impact assessment (HIA). METHODS A participatory HIA was performed using standard World Health Organization methods. A scoping event was held to involve decision makers(More)
BACKGROUND Atrial fibrillation is associated with higher mortality. Identification of causes of death and contemporary risk factors for all-cause mortality may guide interventions. METHODS AND RESULTS In the Rivaroxaban Once Daily Oral Direct Factor Xa Inhibition Compared with Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial(More)
BACKGROUND The aim of the RECCORD registry was to gather real-world UK data on the use of targeted therapies in renal cell carcinoma (RCC) and assess clinical outcomes. Here, demographic and outcome data are presented with the treatment patterns and demographic profile of patients on the registry. PATIENTS AND METHODS Patients were retrospectively(More)
Gastro-Oesophageal Reflux (GOR) is a key problem in Cystic Fibrosis (CF), but the relationship between lung and gastric microbiomes is not well understood. We hypothesised that CF gastric and lung microbiomes are related. Gastric and sputum cultures were obtained from fifteen CF patients receiving percutaneous endoscopic gastrostomy feeding. Non-CF gastric(More)