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In a group of 154 mature normal neonates the authors recorded significantly higher mean alpha-fetoprotein values in children with hyperbilirubinaemia (higher than 205 mumol/l) than in other neonates. The differences were observed also in children of equal gestation age. Development of hyperbilirubinaemia is more probable and indication for phototherapy is(More)
Two groups of fullterm newborns were polygraphically examined. The first group consisted of 10 newborns with hyperbilirubinemia treated by phototherapy, the second group was a control one and consisted also of 10 newborns. The polygrams were made at the age of four days. The length of the sleep cycle, the length of quiet and paradoxical sleep, respiratory(More)
The study of bilirubin photochemical degradation in the presence of riboflavin has shown that, in this case, the primary process is photooxidation during which riboflavin acts as a receptor and bilirubin as a donor of electrons. The reaction proceeds under anaerobic conditions in an equilibrated manner, under aerobic ones as a catalytic process during which(More)
In a group of mature neonates with hyperbilirubinaemia the authors investigated by chromatography, using the HPLC method, levels of bilirubin photoisomers before phototherapy, in the course of phototherapy and after its termination. The configuration isomer 4 Z, 15 E is detected in blood of all icteric neonates already before the onset of treatment in a(More)