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PURPOSE The purpose of this study was to examine in listeners with normal hearing and listeners with sensorineural hearing loss the within- and between-group differences obtained with 4 commonly available speech-in-noise protocols. METHOD Recognition performances by 24 listeners with normal hearing and 72 listeners with sensorineural hearing loss were(More)
BACKGROUND In the Medical Research Council (MRC) COIN trial, the epidermal growth factor receptor (EGFR)-targeted antibody cetuximab was added to standard chemotherapy in first-line treatment of advanced colorectal cancer with the aim of assessing effect on overall survival. METHODS In this randomised controlled trial, patients who were fit for but had(More)
The equivalence was determined for the W-22 and NU No. 6 lists recorded with the same carrier phrase and by the same speaker (Auditec compact disc). For presentation, the lists were interleaved to form lists of 100 words. In Experiment 1, the materials were presented in quiet (0 to 30 dB HL) and in 60 dB SPL speech-spectrum noise (35 to 65 dB HL) at 5 dB(More)
Two descriptive experiments were performed on a version of the Northwestern University Auditory Test No. 6 (NU No. 6) recorded by a female speaker that is included on an audio compact disc recently produced by the Department of Veterans Affairs. In Experiment 1, normative psychometric functions for the female speaker version of the NU No. 6 materials were(More)
Dichotic digit listening was made more difficult by interleaving one-, two-, three-, and four-pair digits within a test list in which the subjects did not know a priori the number of digit pairs presented on a given trial, thereby introducing listener uncertainty. Twenty right-handed (mean age = 26.8 years) and 20 left-handed adults (mean age = 24.0) with(More)
Oxaliplatin, an effective cytotoxic treatment in combination with 5-fluorouracil for colorectal cancer, is associated with sensory, motor and autonomic neurotoxicity. Motor symptoms include hyperexcitability while autonomic effects include urinary retention, but the cause of these side-effects is unknown. We examined the effects on motor nerve function in(More)
Dichotic listening was evaluated in pre-cued and post-cued response conditions using a hierarchical set of one-, two- and three-pair dichotic digit materials. Thirty young adults (mean age 29.1 years) with normal hearing, and 30 older adults in the 60-79-year age range (mean age 68.7 years) with mild-to-moderate sensorineural hearing loss were evaluated.(More)
OBJECTIVES This study compared speech recognition performance on the Northwestern University Auditory Test No. 6 (NU-6) and the Connected Speech Test (CST) for three hearing aid circuits (peak clipping [PC], compression limiting [CL], and wide dynamic range compression [WDRC]) in adults with symmetrical sensorineural hearing loss. The study also questioned(More)
BACKGROUND Pure-tone, air-conduction audiograms notched at 4000 Hz have long been considered the signature configuration for noise-induced hearing loss even though there is an extensive literature that does not mesh with this simple explanation. There are many reports of notched audiograms from individuals with no history of noise exposure and, conversely,(More)
Dichotic listening was evaluated in free-recall and directed-recall (pre-cued, post-cued) response conditions using interleaved one-, two-, and three-pair dichotic digit materials. In the free-recall condition, the subjects recalled in any order the digits presented. In the directed-recall condition, a response task was examined where subjects recalled all(More)