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  • R H Mole
  • 1975
Cancer is naturally very common, and practical questions about the possibility of radiation-induced harm are often questions about what in other contexts would be called background noise. Central to the question of whether small radiation exposures are carcinogenic is the effect of antenatal radiography. A comparison of singleton and twin births with(More)
THE results of a number of workers show a considerable quantitative consistency in the frequency of tumours per unit of radiation dose following exposure of the skin to large doses of ionizing radiation (Hulse, 1962). When low as well as high doses of 204T1 beta particles were used, the dose-response suggested that tumour induction increased according to(More)
The form of the dose-response for induction of malignant diseases in vivo by ionizing radiation is not yet established in spite of its scientific interest and its practical importance. Considerably extended observations have confirmed that the dose-response for acute myeloid leukaemia induced in male CBA/H mice by X-ray exposure is highly curvilinear. The(More)
Acute myeloid leukaemia induction by X- and gamma-rays in 4 mouse strains follows the same dose-response aD2e-lambda D. The (dose)2 interaction disappears within 3 days. AML appears earlier when syngeneic marrow cells are injected 3 days after irradiation, minimum latent period and final frequency remaining unchanged. Dose-responses for brief and protracted(More)
The meanings, past and present, of the word stochastic are discussed and related to the way in which "stochastic" and "non-stochastic" may be used to describe the categories of biological damage from ionizing radiation. "Haplocytic" and "polycytic" are suggested as alternatives: these terms allow a classification according to the numbers of cells involved(More)