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With the method of pH-Stat the adenosinedeaminase-, adenosine-5'-monophosphate deaminase-, cytidine-5'-monophosphate deaminase activities are determined in the nucleus-, mitochondrial-, microsomalfractions and in the cytoplasmatic fractions of the human termplacental and amniotic tissues. The desaminase activities were higher in the amniotic fractions. The(More)
The long-term (2 year) safety and efficacy of barnidipine was assessed in an open-label, dose-titration, multicentre study of 236 patients aged > or = 75 years with a sitting diastolic blood pressure (DBP) > or = 95 mmHg. All eligible patients started treatment with barnidipine 10 mg once daily. After at least 4 weeks treatment, the dose of barnidipine was(More)
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