R.F. Whitcomb

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Measurement of the urinary excretion of lutropin (LH) and follitropin (FSH) and their common free alpha subunit (FAS) assists in monitoring the maturation of the hypothalamic-pituitary-gonadal axis and in understanding the physiology of the pituitary glycoprotein hormones. Here we describe sensitive, specific polyclonal radioimmunoassays for LH and FSH and(More)
GnRH pulse frequency, amplitude, and interpulse interval have all been demonstrated to regulate gonadotropin secretion individually. We tested the hypothesis that the contour of the GnRH pulse also modulates gonadotropin output in 10 men with isolated GnRH deficiency in whom a fixed GnRH dose was administered at a constant physiologic frequency by either(More)
E.A. Freundt in his introductory remarks emphasized the importance of developing improved techniques, not only for the successful isolation of as yet non-cultivable mycoplasmas, but also for the recovery of already established species exhibiting relatively well-defined nutritional requirements. As an example, mention was made of the significantly higher(More)
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