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The research of the Computer/Law Institute at the Vrije Universiteit of Amsterdam on legal expert systems is bundled in the PROLEXS projectl. In the course of this project we were confronted with a number of problems in building legal expert systems. In this paper we describe one of the fundamental problems, the diverse nature of the legal sources, both(More)
1 ABSTRACT This paper discusses the aims of automatic character recognition and the challenges that arabic characters pose to the implementation of a recognition system suitable for this script. The role of neural networks used as classiiers is examined, several neural network architectures are investigated, and their classiication performance is evaluated(More)
The new society was created by and for practitioners of longevity medicine who seek evidence-based information on clinical methods for improving and extending health, vitality and quality of life during aging. Through application of these methods, onset of intrinsic diseases associated with senescence can be delayed and possibly prevented instead of being(More)
Growth hormone (GH) secretion declines during aging. Since GH alters plasma cholesterol (PC) concentrations, it was of interest to determine how GH secretagogues affect age-related hypercholesterolemia. Fischer 344 rats (3 and 14 months old) were co-administered (s.c.) GH releasing hormone (3 micrograms/kg; GHRH) and GH releasing hexapeptide (100(More)
We previously reported the unusual case of a teenage girl stricken with multifocal developmental dysfunctions whose physical development was dramatically delayed resulting in her appearing to be a toddler or at best a preschooler, even unto the occasion of her death at the age of 20 years. Her life-long physician felt that the disorder was unique in the(More)
The concepts of "anti-aging" and "anti-aging medicine" in particular are hotly debated now, both in the mass media and among some researchers. This paper represents an open discussion of anti-aging terms and related ideas by nine leading experts in the field of aging studies, and it describes in detail the arguments presented by both supporters and(More)
In 1932, Bidder postulated that senescence results from "continued action of a (genetic) regulator (of development) after growth ceases (maturation occurs)." A 16-year-old girl who physically appears to be an infant has not been diagnosed with any known genetic syndrome or chromosomal abnormality. The subject's anthropometric measurements are that of an(More)