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Journals and Conferences
Matrix tablets manufactured from a practically insoluble drug using Methocel K4M, Methocel K100LV, and mixtures thereof exhibited non-Fickian dissolution properties governed by both diffusion and erosion (value of diffusional exponent in Peppas's transport equation 0.7). The effects of these two hydroxypropyl methylcellulose (HPMC) varieties were nonlinear… (More)
Tablets manufactured from micronized anhydrous nitrofurantoin exhibited unsatisfactory dissolution properties, whereas excellent results were obtained with unmilled drug material having fine particle size.
A chemical interaction between lisinopril and lactose was demonstrated and quantified in dilute mixtures in the solid state.
The presence of citric acid in the film coating of ranitidine hydrochloride tablets decreased discoloration.
The anomalous acidic properties of the coarse grades of anhydrous calcium hydrogen phosphate are commented and a tentative elucidation of this is proposed.
Tablets containing an angiotensin-converting enzyme inhibitor and either calcium sulphate dihydrate or lactose monohydrate as main excipients (fillers) exhibited similar technical properties and stability.