R. E. Remillard

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Cytosolic phospholipase A2 (cPLA2) catalyzes the selective release of arachidonic acid from the sn-2 position of phospholipids and is believed to play a key cellular role in the generation of arachidonic acid. BMS-229724 (4-[4-[2-[2-[bis(4-chlorophenyl)methoxy]ethyl-sulfonyl]ethoxy]phenyl]-1,1,1-trifluoro-2-butanone) was found to be a selective inhibitor of(More)
We report the discovery of an X-ray transient, observed in outburst with XMM-Newton on March 20, 2003, and with position α = 18h12m27.8s, δ = −181234 (J2000, approximate positional error 2). No known source is present at this position and the source was not detected during published ROSAT or ASCA observations of that region. However, the source may be(More)
We report continuous monitoring of Cygnus X-1 in the 1.3–200 keV band using All-Sky MonitoryRossi X-Ray Timing Explorer and BATSEyCompton Gamma Ray Observatory for about 200 days from 1996 February 21 to early September. During this period, Cygnus X-1 experienced a hard-to-soft and then a soft-to-hard state transition. The low-energy X-ray (1.3–12 keV) and(More)
Native sulfatides, as well as many sulfated glycolipids, have been shown to avidly bind to the selectin receptors. In vivo, native sulfatides significantly block activity in selectin-dependent inflammatory responses. The fact that nonsulfated galactocerebrosides did not inhibit selectin-mediated adhesion identified a critical role for the anionic sulfate(More)
Regular observations by the All Sky Monitor aboard the Rossi X-ray Timing Explorer satellite have yielded well-sampled light-curves with a time baseline of over ten years. We find that up to eight of the sixteen brightest persistent low mass X-ray binaries show significant, possible sinusoidal, variations with periods of order ten years. We speculate on its(More)
The Chandra AO1 HETGS observation of the micro-quasar GRS 1915+105 in the low hard state reveals (1) neutral K absorption edges from Fe, Si, Mg, and S in cold gas, and (2) highly ionized (Fe xxv and Fe xxvi) absorption attributed to a hot disk, disk wind, or corona. The neutral edges reveal anomalous Si and Fe abundances which we attribute to surrounding(More)
We report continuous monitoring of Cygnus X-1 in the 1.3 – 200 keV band using ASM/RXTE and BATSE/CGRO for about 200 days from 1996 February 21 to 1996 early September. During this period Cygnus X-1 experienced a hard-to-soft and then a soft-to-hard state transition. The low-energy X-ray (1.3-12 keV) and high-energy X-ray (20-200 keV) fluxes are strongly(More)
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