Author pages are created from data sourced from our academic publisher partnerships and public sources.
Noninvasive monitoring of drug biodistribution and metabolism: studies with intraarterial Pt-195m-cisplatin in humans.
We have performed a comparative evaluation of systemic (i.v.) and intraarterial (i.a.) cisplatin by using a trace dose of the radiolabeled form of this drug [( 195mPt]cisplatin) to monitor the drug's… Expand
Noninvasive estimation of bound and mobile platinum compounds in the kidney using a radiopharmacokinetic model.
- R. Brechner, D. D’Argenio, R. Dahalan, W. Wolf
- Chemistry, Medicine
- Journal of pharmaceutical sciences
- 1 September 1986
Nephrotoxicity remains a major limitation in the use of cisplatin [cis-diamminedichloroplatinum(II)]. Although several strategies are in use to limit this serious side effect, none is fully… Expand
A New Approach to Organ Pharmacokinetics Using Noninvasive Radionuclide Measurement Methods
Proper chemotherapy requires that the right dose of the right drug be administered to a given patient at the correct rate. This can be achieved if there is proper monitoring of the drug's… Expand