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Professor Weiss states the purpose of his new book with admirable directness: '. . . to describe the various components of the metastatic process ... and to discuss the underlying principles! Although the limitations of animal models are always stressed, experimental studies form a major part of the text. The first chapter is concerned with mechanisms of(More)
BACKGROUND Reducing automobile dependence and improving rates of active transport may reduce the impact of obesogenic environments, thereby decreasing population prevalence of obesity and other diseases where physical inactivity is a risk factor. Increasing the relative cost of driving by an increase in fuel taxation may therefore be a promising public(More)
This paper presents a novel procedure for modeling adjacent device heating effects (thermal coupling) of dielectrically isolated bipolar junction transistors. A new thermal model has been developed for the thermal coupling of multiple devices in an integrated circuit. It also considers the different spacings between adjacent devices. A proposed measurement(More)
overall they are of high standard. Although the authors mention in the preface the concerns regarding the late complications of therapy, these are discussed to a very variable extent in different tumour groups and are not mentioned at all in the discussions on soft tissue sarcomas and Ewing's tumour-two tumours where particularly serious problems have been(More)
"Precancer" is a difficult subject to discuss and an issue of Cancer Surveys, devoted to this topic, is welcome. The approach is selective, with an editorial overview followed by contributions dealing with the cervix uteri, breast, oral cavity, lungs, stomach, large bowel and bladder. A final section discusses some experimental approaches. Emphasis is(More)
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