R. C. S. Sousa

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BACKGROUND Cutaneous leishmaniasis (CL) is treated with parenteral drugs for decades with decreasing rate cures. Miltefosine is an oral medication with anti-leishmania activity and may increase the cure rates and improve compliance. METHODOLOGY/PRINCIPAL FINDINGS This study is a randomized, open-label, controlled clinical trial aimed to evaluate the(More)
Correlations between the genetic diversity of Leishmania infantum (syn. L. chagasi) isolates and their respective geographic origins support the theoretic assumption that visceral leishmaniasis probably originated in the Old World. Because dogs are widely considered to be the main reservoir of this disease, the present study aimed to investigate the degree(More)
Leishmania (Viannia) braziliensis causes three main types of American tegumentary leishmaniasis (ATL), localized cutaneous leishmaniasis (CL), mucosal leishmaniasis (ML), and disseminated leishmaniasis (DL). All forms are observed among individuals of Corte de Pedra, Brazil. We previously used random amplified markers to identify a multiclonal population(More)
Agent orientation appears as a solution for constructing complex systems adapting the requirements identification to cope with agent properties like autonomy, sociability and pro-activeness. Many methodologies were proposed adopting this new paradigm. However, most of them are still in development and therefore need to be adapted. In this work MaSE, an(More)
Amplitude and relative phase measurement of noisy CW signals require appropriate techniques, such as coherent detection, for maximum dynamic range and accuracy. We hereby describe a two channel system, developed for satellite microwave propagation beacon experiments, that comprises a user developed card, a DSP kit and dedicated software. The solution, that(More)
  • Juliana Silva, Adriano Queiroz, +7 authors Albert Schriefer
  • PLoS neglected tropical diseases
  • 2017
BACKGROUND American Tegumentary Leishmaniasis (ATL) caused by Leishmania braziliensis is endemic in Corte de Pedra, Northeast Brazil. Most L. braziliensis infections manifest as localized cutaneous leishmaniasis (CL). Disseminated manifestations include mucosal leishmaniasis (ML), present at a low constant level for several decades, and newly emerging(More)
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