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Many scientific and engineering applications require optimization methods to find more than one solution to multi-modal optimization problems. This paper presents a new particle swarm optimization (PSO) technique to locate and refine multiple solutions to such problems. The technique, NichePSO, extends the inherent unimodal nature of the standard PSO(More)
INTRODUCTION Hyperglycemia represents an independent prognostic factor in critically ill non-diabetic patients but not in those with diabetes. In this context, there is an ongoing debate on the benefit of an intensive insulin therapy, particularly in diabetic patients. We tested the hypothesis that expression of the receptor for advanced glycation(More)
BACKGROUND Clinical effects and outcomes of a single dose etomidate prior to intubation in the intensive care setting is controversial. The aim of this study is to evaluate the association of a single dose effect of etomidate prior to intubation on the mortality of septic cirrhotic patients and the impact of the subsequent use of low dose hydrocortisone. (More)
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