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OBJECTIVE Cisplatin is a standard treatment in advanced, recurrent cervical cancer. Because topotecan is an established treatment in gynecologic malignancies such as ovarian cancer and exhibits nonoverlapping toxicity with cisplatin, a phase II trial was conducted to evaluate the tolerability and antitumor activity of a cisplatin/topotecan doublet in(More)
Visual search performance for tactical symbols was examined with liquid-crystal (LCD) and cathode-ray tube (CRT) displays. Twenty-four adult participants (19 men, 5 women; mean age 41 years) searched for navy tactical display symbols on a map background. LCD and CRT displays of similar size and resolution (52 cm diagonal, 1280 x 1024 pixels) were used.(More)
BACKGROUND Sertoli-Leydig cell tumors (SLCT) constitute only 0.5% of all primary ovarian neoplasms. We report a unique diagnostic method (selective laparoscopic venous sampling) and a rare case of a contralateral second primary tumor. CASE A 14-year-old female presented with hyperandrogenic complaints and an increased serum testosterone. Ovarian origin(More)
OBJECTIVE To describe and evaluate the technique and the clinical outcome of a new modality for the treatment of women with persistent or recurrent pelvic malignancies utilizing surgically (laparotomy or laparoscopic) guided high dose rate (HDR) catheters to complete high dose rate interstitial irradiation therapy (LG-HDRT). METHODS Between 6/2000 and(More)
The effectiveness of intraoperative irrigation with cefoxitin was compared prospectively with that of a short course of intravenous cefoxitin as prophylaxis against endometritis. One hundred three patients who underwent primary cesarean at University Hospital, Jacksonville, Florida, were randomized into two study groups. The first group received(More)
This is a report of a cleft palate-craniofacial team's experience with 768 patients that have had clefting over 22 years, with a primary focus on function and prevention of communication disorders associated traditionally with cleft palate. The treatment philosophy is based on tenets of child development and the dependency of neuropsychobiological(More)
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