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Young adult rabbits have been given methyl mercury salts by subcutaneous injections or by gastric intubation. After 3 daily doses of 7.5 mg/kg by the 8th day moderate to severe ataxia developed, and after 4 doses, severe ataxia. Some of these latter animals might die. This species, therefore, seems to be about twice as sensitive to the neurotoxic properties(More)
  • R A Rodda
  • Journal of the neurological sciences
  • 1981
The clinical features are outlined and the neuropathological changes described in 3 cases (2 adults and 1 child) of Huntington's disease with severe atrophy of the cerebellum. Onset occurred at the ages of 56, 55 and 3 and death at 70, 62 and 6 years, respectively. All cases presented with cerebellar ataxia and this is also recorded in one relative of each(More)
The gross and histological features of 189 parenchymal brain lesions in 57 spontaneously hypertensive stroke prone rats are described. There were 127 lesions many of them cystic, showing evidence of old haemorrhage. Of these, 71 also showed recent haemorrhage and there were 26 lesions showing recent haemorrhage only. There were 21 small focal lesions with(More)
  • Journal of clinical pathology
  • 1953
Rupture of the aorta has become familiar as a cause of rapid death, especially in certain accidents involving modern, fast transport (Helpern, 1952). Although the victims very seldom survive more than an hour (Strassmann, 1947) a case in which death was delayed for 20 days has been described by Rice and Wittstruck (1951). The following case records a(More)