R. A. Gakhokidze

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Water-soluble polysaccharides have been isolated from nine representatives of the Georgian flora belonging to seven families. According to preliminary results two of them contained glucomannans and the others contained acid arabinogalactans. A more detailed study of a polysaccharide from the fruit of the mistletoeViscum album has permitted it to be assigned(More)
The present study investigates antimutagenic and anticytotoxic effect of polyvitamin complex Polijen in laboratory mice. Mutation in mice was induced by pesticide - copper oxychloride 3Cu(OH)2 CuCl2 , which is characterizes by the mutagenic and cytotoxic effect. Introduction of copper oxychloride (dosage 1/2, 1/5, 1/10 LD50) per oral to animals induces(More)
The antimutagenic and anticytotoxic effects of bioactivator - biorag (created by Prof. R. Gakhokidze) in the case of mutations induced by ammonium nitrate (NH(4)NO(3)) were studied on the laboratory mice. The cytogenetic and toxicological methods of investigation were used in our research. Ammonium nitrate is characterized by mutagenic, cytotoxic and(More)
A synthesis of sulfur-containing glycosides based on interaction of allyl derivatives of acetylated carbohydrates-glucose, maltose, and lactose-with phenylsulfenechloride is described. The bactericidal properties of the resulting compounds were studied. Compounds were found to have different levels of inhibitory activity against microorganisms.
This work is devoted to the problem connected with rhodopsin activation. Electrostatic forces involved in photoisomerization of retinal are considered. It is suggested that the repulsion force and rotating moment between electric dipole moments of methyl groups on the C5 and C13 atoms of retinal can promote isomerization upon light absorption because the(More)
S-containing disaccharides play an important role in the vital activity of animals and plants and occupy a special place among carbohydrate derivatives [1]. The present communication reports on the synthesis of the S-containing disaccharides hepta-O-acetyl-1-O-(2-chloro-3phenylthiopropyl)-β-D-maltose and(More)
A new synthesis of certain lactam-containing N-glycosides was developed. 2,3,4,6-Tetra-O-acetyl-β-D-gluco(galacto)pyranosylcaprolactams and 2,3,4,6-tetra-O-acetyl-β-D-gluco(galacto)pyranosylpyrrolidones were synthesized by condensation at room temperature of acetobromoglucose and acetobromogalactose with ɛ-caprolactams and α-pyrrolidone.
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