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In previous studies it has been shown that both bradykinin and histamine increase the formation of 3H-labeled inositol phosphates in adrenal chromaffin cells prelabelled with [3H]inositol and that both these agonists stimulate release of catecholamines by a mechanism dependent on extracellular calcium. Here, we have used mass assays of inositol(More)
The effects of cold-exposure, the hyperthyroid state and a single exercise bout in vivo on the maximal enzyme activities of 6-phosphofructokinase and fructose-1,6-bisphosphatase in vastus lateralis muscle and the rates of fructose 6-phosphate/fructose 1,6-bisphosphate cycling measured in epitrochlearis muscle in vitro were investigated. In all cases(More)
The mechanisms by which N-methyl-D-aspartate (NMDA) receptor activation can modulate muscarinic receptor-stimulated phosphoinositide turnover have been studied in neonatal rat cerebral cortex slices. A maximally effective concentration of carbachol (1 mM) caused a large stimulation of both total [3H]inositol phosphate ([3H]InsPx) accumulation (30-40-fold(More)
Starvation decreases activities of some glycolytic and citric acid-cycle enzymes, and increases those of glucose 6-phosphatase and fructose bisphosphatase, whereas that of glutaminase is unchanged. These findings may be of significance for the control of glucose metabolism in the absorptive cells of the intestine.
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