R. A. Carapellotti

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Physiological disposition of isoergine (d-isolysergamide, iso-LA) obtained from the seeds of Argyreia nervosa (Burm. f.) Bojer were determined in rat liver, brain and plasma. Method of determination involved the extraction of the drug from biological samples and quantitation of the compound by fluorometric analysis. The injection of 5 mg/kg, i.p., of iso-LA(More)
Derivatives of two new and unusual classes of heterocycles, possessing structural similarities to the broad spectrum antibiotic fervenulin, were synthesized and examined for in vitro antimicrobial activity. Only three of 17 mesoionic pyrimido[1,2-b]pyridazine-2,4-diones exhibited evidence of antimicrobial activity while seven of eight mesoionic(More)
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