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Cortical bone grafts were implanted for six months in mature dogs using an osteoperiosteal 3-cm defect in the ulna to evaluate their respective morphometric and physical values compared with autografts. The bone-grafting material included fresh auto- and allografts, frozen and thimerosal preserved allografts, and partially demineralized bone allografts. The(More)
Extensive clinical experience has been built up using orthopaedic implants instrumented with strain gauges connected to a Wheatstone bridge by means of percutaneous leads. This research showed the medical relevance of the monitoring of the deformation of implants as a powerful tool to evaluate nursing and rehabilitation exercises, for tracing dangerous(More)
Twenty pairs of dried macerated femora were submitted to progressive, physiologically oriented loading. The aim of this work was to determine the role of trabecular bone, the importance of the bone mineral density of the femoral shaft, and the importance of the Singh index in the mechanical strength of the femoral neck. By means of an original technique,(More)
The pharmacodynamic activity of (+/-)-1-[4-(2-isopropoxyethoxymethyl)-phenoxy]-3-isopropylamino-2- propranol- hemifumarate (bisoprolol, EMD 33 512) has been investigated under in vitro and in vivo conditions. Bisoprolol was found to be an effective beta-adrenoceptor antagonist, the pA2 values determined against isoprenaline in guinea pig atria and tracheal(More)
In order to assess the potential influence of various physical or chemical treatments on bone grafts, and in particular, on femoral heads to be used as bone grafts, the mechanical symmetry of the femoral head was investigated. Pairs of proximal human femora were harvested and transversally sliced using a coordinate system to orient correctly the head. After(More)
The external fixator provides a mechanical connection between the bone fragments and recording devices or power systems. We have used this characteristic of external fixation since 1965 to record deformations occurring at the fracture site and to measure the mechanical characteristics of fracture healing in more than 500 patients. As in all osteosyntheses,(More)
INTRODUCTION Several authors have reported evidence of loosening of the acetabular component in 14 per cent of cases at 10 years follow-up. To understand this phenomena, parametric studies of the acetabulum have involved finite element analysis, photo elastic models or strain gauges. The differing and sometimes contradictory results were due to the way the(More)
The measurement of fracture healing is a problem before us now; many techniques are now being developed. One of them is strain gauge measurement, allowing control of the development of the callus stiffness. The mathematical models and the experimental controls always had to deal with "preliminary assumptions." Theoretically, the output of a single strain(More)
The morphological and physical aspects of cortical bone autografts implanted in dogs for 1-9 months in two differently located skeletal defects are reported with a twofold aim: to provide a reference system for further comparison with various allografts and to delineate a general pattern of cortical bone graft healing. A 3-cm osteoperiosteal gap was created(More)