R A Bass

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Nonribosomal peptide synthesis is achieved in prokaryotes and lower eukaryotes by the thiotemplate function of large, modular enzyme complexes known collectively as peptide synthetases. These and other multifunctional enzyme complexes, such as polyketide synthases, are of interest due to their use in unnatural-product or combinatorial biosynthesis (R.(More)
Detection of the producers of microcystins and other nonribosomal peptides with molecular probes and the polymerase chain reaction (PCR). This thesis is based on the following articles, which are referred to by their Roman numerals in the text. of toxin-producing cyanobacteria by using an oligonucleotide probe containing a tandemly repeated heptamer. Paper(More)
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