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be a memoryless source with unknown distribution on a finite alphabet of size k. We identify the asymptotic minimax coding redundancy for this class of sources, and provide a sequence of asymptotically mini-max codes. Equivalently, we determine the limiting behavior of the minimax relative entropy min Q max P D(P X kQ X), where the maximum is over all(More)
—For problems of data compression, gambling, and prediction of individual sequences 1 the following questions arise. Given a target family of probability mass functions (1), how do we choose a probability mass function (1) so that it approximately minimizes the maximum regret /belowdisplayskip10ptminus6pt max (log 1 (1) log 1 (1 ^)) and so that it achieves(More)
OBJECTIVE To determine whether anaesthetised patients undergoing surgery could benefit from intraoperative protective ventilation strategies. METHODS MEDLINE, EMBASE and Cochrane Central Register of Controlled Trials (CENTRAL) were searched up to February 2014. Eligible studies evaluated protective ventilation versus conventional ventilation in(More)
BACKGROUND Recent studies showed that sore throat following endotracheal intubation was a common problem following surgery. The objective of this systematic review and meta-analysis of published randomized controlled trials (RCTs) or cohort studies was to estimate whether the size of endotracheal tube (ETT) affects the incidence of postoperative sore throat(More)
Sepsis-associated encephalopathy (SAE) is characterized as brain dysfunction associated with sepsis. In this study we sought to investigate the effects of resveratrol in mice with SAE, as well as its effects in NLRP3 inflammasome and IL-1β, which were critical in the pathogenesis of SAE. SAE was induced in mice via cecal ligation and puncture (CLP), and(More)
Gln49-PLA(2) is a phospholipase A(2) isolated from the Gloydius ussurensis snake venom. In this paper, we studied its effect on the function of neural conduction. Electrophysiological studies demonstrated that Gln49-PLA(2) reduced the amplitude of the action potential and the velocity of nerve conduction on isolated mouse sciatic nerve. Patch clamp(More)
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