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Time‐of‐flight secondary ion mass spectrometry imaging of biological samples with delayed extraction for high mass and high spatial resolutions
Rationale In Time‐of‐Flight Secondary Ion Mass Spectrometry (TOF‐SIMS), pulsed and focused primary ion beams enable mass spectrometry imaging, a method which is particularly useful to map variousExpand
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An Integrative Approach to Decipher the Chemical Antagonism between the Competing Endophytes Paraconiothyrium variabile and Bacillus subtilis.
An integrative approach combining traditional natural products chemistry, molecular networking, and mass spectrometry imaging has been undertaken to decipher the molecular dialogue between the fungusExpand
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Mapping Dicorynia guianensis Amsh. wood constituents by submicron resolution cluster-TOF-SIMS imaging.
The preparation of tropical wood surface sections for time-of-flight secondary ion mass spectrometry imaging is described, and the use of delayed extraction of secondary ions and its interest for theExpand
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Analysis of Chemotherapeutic Drug Delivery at the Single Cell Level Using 3D-MSI-TOF-SIMS
AbstractIn this work, we show the advantages of label-free, tridimensional mass spectrometry imaging using dual beam analysis (25 keV Bi3+) and depth profiling (20 keV with a distribution centered atExpand
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Multimodal Imaging Mass Spectrometry to Identify Markers of Pulmonary Arterial Hypertension in Human Lung Tissue using MALDI-ToF, ToF-SIMS and Hybrid SIMS.
Pulmonary arterial hypertension (PAH) is a rare and deadly disease affecting roughly 15-60 people per million in Europe with a poorly understood pathology. There are currently no diagnostic tools forExpand
Imagerie de substances naturelles par spectrométrie de masse
Cette these a ete consacree a l’amelioration de methodes en imagerie par spectrometrie de masse, et a leur utilisation pour l’analyse in situ de substances naturelles. Une premiere partie a eteExpand
Study of wood metabolites by submicron resolution Cluster-TOF-SIMS imaging.
Heartwood formation study is of great interest in the di scovery of new natural compounds. It usually follows the death of parenchyma cells and tyloses formation. Cell apoptosis seems to beExpand
An integrative approach to decipher the chemical communication between the competing endophytes Paraconiothyrium variabile and Bacillus subtilis
To interact with one another and respond to environmental cues, microorganisms communicate with their own chemical languages using a wide range of extracellular signals and cellular responses.Expand