Quansheng Zhang

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Although zinc finger E-box binding homeobox 1 (ZEB1) has been identified as a key factor in the regulation of breast cancer differentiation and metastasis, its potential role in modulating tumor angiogenesis has not been fully examined. Here, we present the novel finding that conditioned medium derived from ZEB1-expressing MDA-MB-231 cells significantly(More)
The photosynthesis and growth responses of Sargassum thunbergii germlings to different light intensities (10, 60, and 300 μmol photons m−2 s−1) were investigated. Maximum photochemical efficiency (F v/F m), rapid light curves (RLCs), and photochemical and non-photochemical quenching (qP and NPQ) were estimated by a pulse amplitude-modulated fluorometer. The(More)
Their antiangiogenic effects make vascular endothelial growth factor receptor 2 (VEGFR2) inhibitors useful for cancer treatment. However, most of these drugs have unexpected adverse side effects. Here, we show that the novel VEGFR2 inhibitor YLL545 suppressed tumor angiogenesis and growth in triple-negative breast cancer without adverse effects. YLL545(More)
An ecological demographic study was conducted from January to December 2009 at Changshan Island on the northern side of Shandong Peninsula, China. The study investigated stem regeneration and the resource trade-off between sexual reproduction and vegetative regeneration of the brown alga Sargassum thunbergii at the individual thallus level. Stem(More)
The air conditioning system is one of the largest ancillary loads in passenger cars, with considerable effects on the vehicle fuel consumption. In this scenario, the optimization and control of the A/C system actuators has an important role in reducing the parasitic load of the A/C compressor on the engine. In this scenario, this paper presents an(More)
Cancer stem cells (CSCs) are a subpopulation of cancer cells believed to be implicated in cancer initiation, progression, and recurrence. Here, we report that ectopic expression of zinc finger E-box binding homeobox 1 protein (ZEB1) results in the acquisition of CSC properties by breast cancer cells, leading to tumor initiation and progression in vitro and(More)
Antiestrogen resistance is a major obstacle to endocrine therapy for breast cancers. Although reduced estrogen receptor-α (ER-α) expression is a known contributing factor to antiestrogen resistance, the mechanisms of ER-α downregulation in antiestrogen resistance are not fully understood. Here, we report that ectopic zinc-finger E-box binding homeobox 1(More)
The responses of the early development of Laminaria japonica collected from Kiaochow Bay in China to enhanced ultraviolet-B radiation (UV-B, 280–320 nm) were studied in the laboratory. The low UV-B radiations (11.7–23.4 J·m−2·d−1) had no significant effects on zoospores attachment, but when the UV-B dose > 35.1 J·m−2·d−1 the attachment decreased(More)
This paper investigates an output tracking problem for the vapor compression cycle in automotive Air Conditioning (A/C) systems using Linear Parameter Varying (LPV) techniques. Stemming from a recently developed first-principle A/C model, Jacobian linearization is first exploited to develop an LPV-based model that is nonlinearly dependent on time-varying(More)