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Maresin-like lipid mediators are produced by leukocytes and platelets and rescue reparative function of diabetes-impaired macrophages.
In conclusion, maresin-L ameliorates Mf inflammatory activation and has the potential to suppress the chronic inflammation in diabetic wounds caused by activation of Mfs and potentially offer a therapeutic option for better treatment of diabetic wounds. Expand
14S,21R-dihydroxy-docosahexaenoic acid treatment enhances mesenchymal stem cell amelioration of renal ischemia/reperfusion injury.
- H. Tian, Yan Lu, Shraddha P Shah, Quansheng Wang, Song‐Pyo Hong
- Biology, Medicine
- Stem cells and development
- 1 May 2012
Using a murine model of renal ischemia/reperfusion (I/R) injury, it is found that treatment with 14S,21R-diHDHA enhanced MSC amelioration of renal I/R injury. Expand
Neuroprotectin/protectin D1: endogenous biosynthesis and actions on diabetic macrophages in promoting wound healing and innervation impaired by diabetes.
- Song‐Pyo Hong, H. Tian, +6 authors N. Bazan
- American journal of physiology. Cell physiology
- 1 December 2014
NPD1 appears to be a MΦs-produced factor that accelerates diabetic wound healing and promotes MΩ pro-healing functions in diabetic wounds. Expand
Long-term infection of SARS-CoV-2 changed the body's immune status
To investigate the immune responses after infection of SARS-CoV-2 in non-critical patients may help to better understand the disease progression, specific antibodies, immune cells, and cytokine changes between the hospitalized and discharged patients are compared. Expand
SGK1-mediated Fibronectin Formation in Diabetic Nephropathy
- Y. Feng, Quansheng Wang, Yumei Wang, B. Yard, F. Lang
- Cellular Physiology and Biochemistry
- 1 November 2005
SGK1 is upregulated in diabetic nephropathy and actively participates in the stimulation of matrix protein deposition in this common deleterious complication of diabetic hyperglycemia. Expand
A novel simple scoring model for predicting severity of patients with SARS‐CoV‐2 infection
A simple prediction model may provide health‐care workers with a practical method and could positively impact decision‐making with regard to deteriorating patients and an effective scoring system to predict the severity of COVID‐19 patients is proposed. Expand
Obesity is a potential risk factor contributing to clinical manifestations of COVID-19
It is suggested that obesity contributes to clinical manifestations and may influence the progression and prognosis of COVID-19 and it is considered as a potential risk factor of the prognosis and special medical care should be performed in obesity patients with CO VID-19 during hospitalization and later clinical follow-up. Expand
[Dracorhodin perchlorate inhibit high glucose induce serum and glucocorticoid induced protein kinase 1 and fibronectin expression in human mesangial cells].
- Yifeng Xie, Quansheng Wang, Jianguo Liu, Jiwen Xie, K. Xue, Qing Tang
- Chemistry, Medicine
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao…
- 1 August 2010
Dracorhodin perchlorate can inhibit high glucose-induced serum and glucocorticoid induced protein kinase 1 (SGK1) and fibronectin(FN) expression in human mesangial cells, and this may be part of the mechanism of preventing and treating renal fibrosis of DN. Expand
Immunohistological Localization of Endogenous Unlabeled Stem Cells in Wounded Skin
- Song‐Pyo Hong, B. Alapure, Yan Lu, H. Tian, Quansheng Wang
- Biology, Medicine
- The journal of histochemistry and cytochemistry…
- 7 January 2014
The feasibility of using immunohistological staining to determine the location of SCs in wounded skin and the intracellular distribution of their molecular markers is demonstrated. Expand
MiR-155 contributes to intestinal barrier dysfunction in DSS-induced mice colitis via targeting HIF-1α/TFF-3 axis
The results suggest that miR-155 contributes to DSS-induced colitis by promoting intestinal barrier dysfunction and inhibiting the HIF-1α/TFF-3 axis. Expand