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Human respiratory syncytial virus (RSV) is the major cause of lower respiratory tract infections in children ,2 years of age. Little is known about RSV intra-host genetic diversity over the course of infection or about the immune pressures that drive RSV molecular evolution. We performed whole-genome deep-sequencing on 53 RSV-positive samples (37 RSV(More)
BACKGROUND Despite a high burden of respiratory syncytial virus (RSV) infections among children, data on demographic and clinical characteristics of RSV are scarce in low and middle income countries. This study aims to describe the viral etiologies, the demographic, epidemiological, and clinical characteristics of children under two years of age who were(More)
Feature-based detection techniques have been advocated for robust spectrum sensing in cognitive radios. Cognitive radios must be able to train themselves to identify the features for a specific primary user at a given channel, time or location. However, `in-the-field' training relies on signal observations where there is uncertainty about whether or not it(More)
Most insights into the cascade of immune events following acute respiratory syncytial virus (RSV) infection have been obtained from animal experiments or in vitro models. Here we investigated host gene expression profiles in nasopharyngeal swabs (NP) and whole blood samples during natural RSV and rhinovirus (hRV) infection (acute versus early recovery(More)
This paper considers the problem, in the context of cognitive radio systems, of identifying the spectral occupancy of a signal, where its bandwidth is only a subset of the total bandwidth of interest. It is argued that traditional detection approaches need to be extended to cater for arbitrary radio environments that are not channelized in a way that is(More)
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