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Acne vulgaris can affect both adolescents and adults. The pathogenesis of acne is multifactorial and involves overproduction of sebum, an abnormal follicular keratinization process, proliferation of Propionibacterium acnes, and hormonal and immunologic factors. Clinical manifestations of acne range from noninflammatory comedones to inflammatory papules,(More)
Some of the most successful algorithms for satisfiability, such as Walksat, are based on random walks. Similarly, local search algorithms for solving constraint optimization problems benefit significantly from randomization. However, well-known algorithms such as stochas-tic search or simulated annealing perform a less directed random walk than used in(More)
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