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OBJECTIVE To reconstitute an Alzheimer's disease model by administering bradykinin (BK) or cyclosporine A (CSA) to the rat hippocampus. METHODS BK or CSA was administered to the rat hippocampus using a stereotaxic apparatus. The behavior of the rats was observed with an electronic attack jump platform. The phosphorylation of Tau protein was examined(More)
BACKGROUND The purpose of this study is to elucidate the association between α-synuclein (SNCA) polymorphisms and the risk of Alzheimer's disease (AD). METHODS The PCR-RFLP was applied to detect SNCA gene rs6532190, rs3775430, and rs10516846 polymorphisms in 98 AD patients and 105 healthy elderly. RESULTS The GG frequency of rs10516846 was evidently(More)
This paper is concerned with the guaranteed cost control for continuous-time singular Markovian jump systems with time-varying delay. Without using the free weighting matrices method, a delay-range-dependent condition is derived in terms of strict linear matrix inequality (LMI), which guarantees that the singular system is regular, impulse free and(More)
This paper is concerned with the problem of exponential stability for a class of stochastic neural networks with Markovian switching and mode-dependent interval time-varying delays. A novel Lyapunov-Krasovskii functional is introduced with the idea of delay-partitioning, and a new exponential stability criterion is derived based on the new functional and(More)
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